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Grey's Anatomy - Season 5 Episode 22 : What a Difference a Day Makes (2025)

Trailer

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms.

Networks:ABC

Genre: Drama

Casts: Ellen Pompeo, Chandra Wilson, James Pickens Jr., Kevin McKidd, Caterina Scorsone, Camilla Luddington, Kim Raver, Jason George, Chris Carmack, Anthony Hill, Adelaide Kane